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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PUF60
All Species:
30.3
Human Site:
Y499
Identified Species:
51.28
UniProt:
Q9UHX1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHX1
NP_001129505.1
559
59875
Y499
A
V
N
R
V
I
I
Y
Q
E
K
Q
G
E
E
Chimpanzee
Pan troglodytes
XP_528257
640
68531
Y580
A
V
N
R
V
I
I
Y
Q
E
K
Q
G
E
E
Rhesus Macaque
Macaca mulatta
XP_001087975
560
59928
Y500
A
V
N
R
V
I
I
Y
Q
E
K
Q
G
E
E
Dog
Lupus familis
XP_856919
535
57780
Y475
A
V
N
R
V
I
I
Y
Q
E
K
Q
G
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3UEB3
564
60230
Y504
A
V
N
R
V
I
I
Y
Q
E
K
Q
G
E
E
Rat
Rattus norvegicus
XP_001071005
563
60102
Y503
A
V
N
R
V
I
I
Y
Q
E
K
Q
G
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511498
531
58636
I484
E
E
E
D
A
E
I
I
V
K
I
F
V
E
F
Chicken
Gallus gallus
NP_001026551
366
38878
P320
P
A
L
T
L
A
Q
P
L
G
A
L
P
Q
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6IQE0
516
55402
V470
E
D
D
A
E
I
I
V
K
I
F
V
E
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T6B9
637
67921
F574
T
V
S
R
V
I
I
F
N
E
K
Q
T
E
N
Honey Bee
Apis mellifera
XP_001121000
541
59288
Y480
V
V
E
R
V
I
I
Y
N
E
R
Q
S
E
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785572
595
63329
Y535
T
V
N
R
V
V
I
Y
Q
E
R
Q
G
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42698
387
42300
R341
R
I
F
V
Q
F
S
R
P
E
E
T
T
K
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S6N6
764
82299
F682
Q
I
I
G
E
N
L
F
P
K
I
Q
A
I
Q
Conservation
Percent
Protein Identity:
100
86.7
99.8
94.9
N.A.
97.8
97.8
N.A.
76.5
63.1
N.A.
68.3
N.A.
45.8
54.3
N.A.
53.2
Protein Similarity:
100
87
99.8
95.1
N.A.
98.2
98.2
N.A.
80.6
64.4
N.A.
76.2
N.A.
58.2
68.6
N.A.
65.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
0
N.A.
13.3
N.A.
60
60
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
13.3
N.A.
26.6
N.A.
73.3
73.3
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
N.A.
20
Protein Similarity:
N.A.
N.A.
N.A.
39.3
N.A.
36.6
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
8
0
8
8
8
0
0
0
0
8
0
8
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
8
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
15
8
15
0
15
8
0
0
0
72
8
0
8
72
50
% E
% Phe:
0
0
8
0
0
8
0
15
0
0
8
8
0
8
8
% F
% Gly:
0
0
0
8
0
0
0
0
0
8
0
0
50
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
15
8
0
0
65
79
8
0
8
15
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
15
50
0
0
8
0
% K
% Leu:
0
0
8
0
8
0
8
0
8
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
50
0
0
8
0
0
15
0
0
0
0
0
8
% N
% Pro:
8
0
0
0
0
0
0
8
15
0
0
0
8
0
0
% P
% Gln:
8
0
0
0
8
0
8
0
50
0
0
72
0
8
8
% Q
% Arg:
8
0
0
65
0
0
0
8
0
0
15
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
8
0
0
0
0
0
8
0
8
% S
% Thr:
15
0
0
8
0
0
0
0
0
0
0
8
15
0
0
% T
% Val:
8
65
0
8
65
8
0
8
8
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _